Figure 2
From: Deletion of Pdcd5 in mice led to the deficiency of placenta development and embryonic lethality
Developmental defects in the labyrinth and junctional zones in Pdcd5–/– placentas. (a–c) H&E staining of Pdcd5+/+ and Pdcd5–/– placentas at E10.5 (a), E12.5 (b) and E13.5 (c). The layers of the placental architecture are labeled: decidua basalis (DB), junctional zone (JZ) and labyrinth zone (LZ). (d) H&E staining of the LZ of Pdcd5+/+ and Pdcd5–/– placentas at E12.5. Vessels were separated by erythrocytes of maternal blood sinuses (asterisks) and fetal vessels (arrows). (e) Histogram shows the ratio of maternal vessels/fetus from Pdcd5+/+ and Pdcd5–/– LZ at E10.5 and E12.5. Three placentas from each genotype and five different sections from each placenta were analyzed. Data are means±S.D. ***P<0.001. (f) H&E staining of the JZ of Pdcd5+/+ and Pdcd5–/– placentas at E12.5. (g and h) Histogram shows the number (g) and nucleus size (h) of TGC from Pdcd5+/+ and Pdcd5–/– JZ at E10.5 and E12.5. Three placentas from each genotype and five different sections from each placenta were analyzed. Data are means±S.D. ***P<0.001, **P<0.01
