Figure 1 | Cell Death & Disease

Figure 1

From: RETRACTED ARTICLE: Deregulated AJAP1/β-catenin/ZEB1 signaling promotes hepatocellular carcinoma carcinogenesis and metastasis

Figure 1

AJAP1 is downregulated in human HCC and negatively correlates with metastasis of HCC. (a) Representative immunohistochemical detection of AJAP1 in tissue microarrays of normal liver tissue and different grades of HCC. Scale bar=100 μm. (b) Percentage of patients with high and low AJAP1 expression according to the following clinical parameters: tumor size (cm), tumor stage (I–II and III–IV), lymph node status (N0 or N1), and metastasis status (M0 or M1). (c) Western blot analysis of HCC and matched non-tumorous tissues from a different cohort. (d) Western blot analysis of AJAP1 expression in L02 and various HCC cell lines, and relative AJAP1 mRNA levels in L02 and HCC cell lines as detected by real-time PCR. The data are expressed as mean±S.D. of three independent experiments. *P<0.05; **P<0.01; ***P<0.001. T: tumor; N: normal tissue

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