Figure 1 | Cell Death & Disease

Figure 1

From: Human MSCs promotes colorectal cancer epithelial–mesenchymal transition and progression via CCL5/β-catenin/Slug pathway

Figure 1

TNF-α aggravates the promotive effect of hMSCs on colon cancer cell proliferation. (a) Conditioned media from hMSCs promotes the proliferation of CRC cell lines. HT29, Lovo, Caco2, and IEC-18 cells were cultured in the CM/TCM collected from hMSCs or serum-free media (NC) for 6 days, then cell proliferation was assessed using the MTT assay. The experimental procedure was repeated for three times, **P<0.01 versus control, ***P<0.001 versus control, #P<0.05 versus hMSCs; (b) Effects of hMSC-CM/TCM on morphological change of HT29 and Lovo cells after cocultured with untreated hMSCs or TNF-α-treated-hMSCs for 4 days (scale bar, 500 μm)

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