Figure 5 | Cell Death & Disease

Figure 5

From: miR-146a facilitates osteoarthritis by regulating cartilage homeostasis via targeting Camk2d and Ppp3r2

Figure 5

The miR-146a delivery into articular chondrocytes impacted substantially on OA development. (a) Schematic diagram illustrating the design of the OA therapeutic experiment. (b and c) OARSI score (b) and Safranin O and fast green staining (c) of knee joint cartilage harvested from the indicated groups. F, femur; T, tibia. Scale bars, 100 μm. (d and e) Immunohistochemical staining and quantitative analysis of the percentage of Col10a1-positive chondrocytes in knee joint cartilage harvested from the indicated groups. n=8–9 per group in a-e. Scale bars, 100 μm. Data are the mean±S.D. *P<0.05, **P<0.01 (Mann–Whitney test)

Back to article page