Figure 1 | Cell Death & Disease

Figure 1

From: WDR79 promotes the proliferation of non-small cell lung cancer cells via USP7-mediated regulation of the Mdm2-p53 pathway

Figure 1

WDR79 interacts with USP7. (a) The predicted functional domains of WDR79 are shown (U: USP7 binding site). (b) A549 and H1299 cells were fixed and incubated with anti-WDR79 and anti-USP7 antibodies, followed by staining with DyLight 594 or Dylight 488-conjugated IgG. DAPI was used for nuclei staining (bars, 30 μm). (c-e) A549 cells transfected with the indicated constructs or H1299 cells were lysed and lysates were subject to immunoprecipitation with anti-Flag (c), anti-WDR79 (d), or anti-USP7 (e) antibodies. The immunoprecipitates were then blotted with the indicated antibodies

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