Figure 7

WDR79 promotes NSCLC cell proliferation via USP7. (a) A549 cells infected with lentivirus encoding the indicated shRNA were transfected with the indicated constructs. Cell proliferation was analysed with MTT at the indicated time points. (n=3; *P<0.05). (b) A schematic illustration of the working model that WDR79 promotes the proliferation of NSCLC cells via USP7-mediated regulation of the Mdm2-p53 pathway