Figure 3
From: Knockout of Eva1a leads to rapid development of heart failure by impairing autophagy
Effects of Eva1a deficiency on cardiac hypertrophy. (a) The hearts of Eva1a deficient mice were enlarged on gross morphology. Haematoxylin and eosin (H&E) staining of heart sections. Scale bar=1 mm or 50 μm. (b) The ratio of heart weight to body weight (HW/BW) did not significantly differ between Eva1a-deficient mice and the other mice (**P<0.01, n=9). (c) The ratio of lung weight to body weight (LW/BW) was significantly different between Eva1a-deficient mice and the other mice (*P<0.05, n=9). (d) Measurements of two-dimensional cardiomyocyte cross-sectional areas (*P<0.05, n=4). (e and f) Analysis of hypertrophy markers Bnp (e) and Anp (f) by qRT-PCR (*P<0.05, **P<0.01, n=5)
