Figure 1 | Cell Death & Disease

Figure 1

From: Cryptotanshinone inhibits human glioma cell proliferation in vitro and in vivo through SHP-2-dependent inhibition of STAT3 activation

Figure 1

Effects of CTS on the proliferation and cell cycle of glioma cell lines. (a) C6, U251, T98G or U87 cells were treated with different doses of CTS (0–20 μM) for the indicated time. Cell growth was measured by MTT assay. Data are expressed as mean±S.E.M.; n=3 for each group. (b) The proliferation of U251, T98G or U87 cells treated with different doses of CTS for 48 h was measured by BrdU cell proliferation assay. Data are expressed as mean±S.E.M.; n=3 for each group. ***P<0.001 versus control group. (c) Representative flow cytometry images of cell cycle analysis of U251 cells treated with indicated concentrations for 24 h. (d) The G0/G1, S and G2/M fractions were measured. Data are expressed as mean±S.E.M.; n=3 for each group. *P<0.05; **P<0.01 versus control group

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