Figure 6 | Cell Death & Disease

Figure 6

From: Cryptotanshinone inhibits human glioma cell proliferation in vitro and in vivo through SHP-2-dependent inhibition of STAT3 activation

Figure 6

Immunohistochemical characterization of mouse glioma. (a) Immunohistochemical characterization of mouse glioma. Immunohistochemical staining with antibodies against p-STAT3 (Tyr705), Ki67 and glial fibrillary acidic protein (GFAP). Note the proliferation activity in brain tissue by Ki67-positive tumor cells. GFAP staining shows reactive gliosis in the brain tissue adjacent to the tumor. Scale bar, 50 μm. (b) The levels of nuclear p-STAT3 (Tyr705) were quantified. Data are expressed as mean±S.E.M., n=5 for each group. *P<0.05 versus Model control group

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