Figure 5

Effect of photo-activation on D112-induced cell death. SK-BR-3 cells were treated with 1 μg/ml D112 for 1 h, washed, and photo-activated for the indicated times (10-60 s). Representative images are shown at 0 and 3 h incubation. Morphological cell death by apoptosis (blue arrow) or necrosis (red arrow) is indicated. Scale bar, 20 μm