Figure 1 | Cell Death & Disease

Figure 1

From: Autophagy blockade and lysosomal membrane permeabilization contribute to lead-induced nephrotoxicity in primary rat proximal tubular cells

Figure 1

Expression of the autophagy marker protein LC3-II in Pb-exposed rPT cells. Cells were incubated with increasing doses of Pb for 3 h (a), 6 h (b) and 12 h (c) to assess the protein levels of LC3-II. (d) Cells were treated with 0.5 μM Pb for different time periods to determine the protein levels of LC3-II. Upper panels: representative western blot images; lower panels: quantitative analysis of protein levels (mean±S.E.M., n=4). ns, not significant, *P<0.05, **P<0.01, as compared with control

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