Figure 3 | Cell Death & Disease

Figure 3

From: Autophagy blockade and lysosomal membrane permeabilization contribute to lead-induced nephrotoxicity in primary rat proximal tubular cells

Figure 3

Pb enhanced autophagosome–lysosome fusion in rPT cells. Cells were treated with 0.5 μM Pb or 1 μM TG (negative control) for 12 h or incubated with EBSS medium for 2 h (positive control), then successively immunostained with LC3, LAMP-1 and nuclei were stained with DAPI. Representative confocal images are shown and panels on the bottom are higher-magnification images of the cropped regions

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