Figure 4 | Cell Death & Disease

Figure 4

From: Inhibition of cancer growth in vitro and in vivo by a novel ROS-modulating agent with ability to eliminate stem-like cancer cells

Figure 4

LBL21 regulated mitochondrial function and cell cycle. (a) The change of MTP after treatments of indicated drugs at 10 μM, analyzed by flow cytometry using fluorescent dye Rhodamine-123. Percentage numbers showing Rhodamine-123-negative cell fraction. (b) The change of mitochondrial mass after treatments of indicated drugs at 10 μM, determined by Mito Tracker Green staining. (c) The oxygen consumption rate after treatments of indicated drugs at 10 μM for 6 h at 37 °C, measured using a Clark-type oxygen electrode. Numbers indicate quantitative O2 consumption rates. (d) Effect of PEITC and LBL21 at 10 μM on the cell cycle of cancer cell lines for 24 h. Cellular DNA contents were measured by flow cytometry. The numbers indicate the normalization of each phase of cell cycle

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