Figure 2
From: Heme oxygenase-1 derived carbon monoxide suppresses Aβ1–42 toxicity in astrocytes
Aβ1–42 does not dramatically alter [Ca2+]i in astrocytes. (a) Example microfluorimetric measurements of [Ca2+]i in astrocytes under control conditions, or exposed to Aβ1–42 or Aβ42-1 as indicated, for 24 h. Scale bars apply to all traces. In each case, for the period indicated by the grey area, extracellular Ca2+ was replaced with 1mM EGTA. (b) Mean±S.E.M. levels of [Ca2+]i measured in 8–9 recordings under normal conditions (left), during exposure to Ca2+-free solution (containing 1 mM EGTA; middle) and following replacement of Ca2+ in the perfusate (right). Significance: *P<0.05; **P<0.01; ***P<0.001 as compared with controls
