Figure 1 | Cell Death & Disease

Figure 1

From: Reduced brain UCP2 expression mediated by microRNA-503 contributes to increased stroke susceptibility in the high-salt fed stroke-prone spontaneously hypertensive rat

Figure 1

Characterization of brain UCP2 gene and protein expression upon JD in SHRSR, SHRSP and in the two SHRSR/SHRSP-STR1/QTL stroke congenic lines (4 weeks of dietary regimen). (a) UCP2 expression in the two parental lines upon either RD or JD; n=7 for each line for each treatment. ***P<0.0001 for JD versus RD fed SHRSP, and for JD-fed SHRSP versus JD-fed SHRSR. (b) WB of UCP2 expression in RD and JD-fed SHRSR, with corresponding densitometric analysis. ***P<0.0001 for JD versus RD. (c) WB of UCP2 expression in RD and JD-fed SHRSP, with corresponding densitometric analysis. ***P<0.0001 for JD versus RD. (d) UCP2 expression in the SHRSP-derived stroke congenic line upon RD or JD; n=6 for each treatment. (e) WB of UCP2 expression in the SHRSP-derived stroke congenic line upon RD or JD. **P<0.001 for JD versus RD. (f) UCP2 expression in the SHRSR-derived stroke congenic line upon RD or JD. n=6 for each treatment. **P<0.001 for JD versus RD. (g) WB of UCP2 expression in the SHRSR-derived stroke congenic line upon RD or JD. **P<0.001 for JD versus RD

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