Figure 7
CC1-EGFP in BLA neurons inhibited mediated BDNF signaling transmission from the BLA to IL. (a) Graphic displaying the method of BDNF and virus injection. (b,c) Representative immunoblots and relative gray density analysis of p-TrkB. Microinjection of BDNF into the BLA induced a rapid increase in TrkB phosphorylation both in the BLA and IL within 20 min, and the increase in TrkB phosphorylation in the IL was blocked by CC1-EGFP expression in the BLA. Data are shown as the mean±S.E.M. (n=3 per group, *P<0.05 compared with the vehicle-treated EGFP group; #P<0.05 in the IL compared with the BDNF-treated EGFP group)
