Figure 8 | Cell Death & Disease

Figure 8

From: Pre-synaptic TrkB in basolateral amygdala neurons mediates BDNF signaling transmission in memory extinction

Figure 8

Work model. Pre-synaptic TrkB of BLA neurons mediated BDNF signaling transmission in fear memory extinction. Infusion of CC1-EGFP into the BLA region inhibits TrkB axonal anterograde transport and reduces its location at pre-synapse. Then, CC1-EGFP overexpression at the BLA impairs memory extinction by interrupting BDNF self-feedback system which depends on the pre-synaptic TrkB of BLA neurons

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