Figure 1 | Cell Death & Disease

Figure 1

From: The BH3-only proteins BIM and PUMA are not critical for the reticulocyte apoptosis caused by loss of the pro-survival protein BCL-XL

Figure 1

Acute loss of BCL-XL causes severe anaemia. Bclxfl/fl;RosaCreERT2Ki/+ mice and control Bclxfl/fl mice were treated with tamoxifen (TAM) to induce Bclx gene deletion. After 1 month (a) blood analysis was performed and (b) spleen weight and cellularity were determined. n=5–6. Data are presented as mean±S.E.M. Significant P-values are shown, unpaired Students t-test

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