Figure 2

MIAT knockdown attenuates myocardial hypertrophy and apoptosis in diabetic rats. (a,c) Left ventricular tissue was stained with hematoxylin-eosin and myocyte cross-sectional area was calculated. (b,d) Cardiomyocyte apoptosis was determined by TUNEL staining and the apoptotic index was calculated. *P<0.05 compared with control; #P<0.05 compared with DM+Scr-shRNA (n=5 per group)