Figure 2 | Cell Death & Disease

Figure 2

From: MET/SMAD3/SNAIL circuit mediated by miR-323a-3p is involved in regulating epithelial–mesenchymal transition progression in bladder cancer

Figure 2

Forced expression of miR-323a-3p inhibits the motility of T24 and UM-UC3 cell lines. (a) A trans-well assay revealed an evident inhibition of migration and invasion of T24 and UM-UC3 cell lines transfected with miR-323a-3p (50 nM). (b) The representative micrograph of trans-well assay was calculated. (c) A wound healing assay showed the consistent inhibition of motility in T24 cell lines. (d,e) Western blot analysis confirmed that miR-323a-3p (50 nM) inhibited EMT and AKT/GSK-3β/SNAIL signaling-related proteins in T24 and UM-UC-3 cell lines. Error bars represent the S.E. obtained from three independent experiments; *P<0.05. Photographs of trans-well assay were obtained under × 10 objective

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