Figure 3
From: Keratin 23 promotes telomerase reverse transcriptase expression and human colorectal cancer growth
KRT23 promoted hTERT expression. (a and b) Downregulation of hTERT mRNA and protein expression by siKRT23 were analyzed by RT-PCR and western blot in LoVo cells. Luciferase activity (c) and telomerase activity (d) were measured after transfection with siKRT23-1/3 in LoVo cells. Upregulation of hTERT mRNA and protein expression by LV-KRT23 were analyzed by RT-PCR (e) and western blot (f) in RKO cells. Luciferase activity (g) and telomerase activity (h) were detected after infection of RKO cells with LV-KRT23
