Figure 4 | Cell Death & Disease

Figure 4

From: miR-125a-3p/FUT5-FUT6 axis mediates colorectal cancer cell proliferation, migration, invasion and pathological angiogenesis via PI3K-Akt pathway

Figure 4

The miR-125a-3p/FUT5-FUT6 axis regulates the invasion and angiogenesis ability of CRC cells. (aand b) Transwell assays showed that SW480 cells transfected with anti-miR-125a-3p or FUT5 or FUT6, exhibited increased invasive ability. (c and d) The expression of miR-125a-3p-mimics, FUT5 shRNA or FUT6 shRNA reduced the invasion ability of SW620 cells. According to an endothelial tube formation assay, (e and f) the length of tubes was significantly increased in the anti-miR-125a-3p, FUT5 or FUT6 group, and (gand h) an opposite result was found with the miR-125a-3p-mimics, FUT5 shRNA or FUT6 shRNA group (*P<0.05)

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