Figure 4
From: Human type H vessels are a sensitive biomarker of bone mass
Change of type H vessels in osteoporotic mice. (a–f) Tibia immunostaining for CD31 (green), Endomucin (red), Osterix (gray), and DAPI (blue) of Sham (a–b), OVX (c–d), and OVX+DFO (e–f) group mice. Lines in b, d, and f indicate the boundary of the metaphysis and growth plate. (g–i) Micro-CT 3D reconstructed images of cancellous bone from the Sham (g), OVX (h), and OVX+DFO (i) mice. (j–n) Quantification of the BMD and trabecular index of bone from the Sham, OVX, and OVX+DFO mice. Graphs represent mean±S.D.; *P<0.05; **P<0.01; Scale bar: 200 μm (e), 100 μm (f)
