Figure 3 | Cell Death & Disease

Figure 3

From: MiR-30c regulates cisplatin-induced apoptosis of renal tubular epithelial cells by targeting Bnip3L and Hspa5

Figure 3

The assessment of apoptosis in HK-2 and NRK-52E cells treated with cisplatin and inhibitors or mimics of miR-30 c. (a and b) HK-2 cells (a) or NRK-52E cells (b) were treated with mimics of miR-30c in the absence/presence of 10 μM cisplatin for 24 or 48 h before flow cytometry analysis (left). The bar chart (right) shows the ratios of apoptosis cell numbers between the groups treated with the negative control mimic, miR-30c mimic, negative control mimic+cisplatin or miR-30c mimic+cisplatin. (c and d) HK-2 cells (c) or NRK-52E cells (d) were treated with inhibitors of miR-30c in the absence/presence of 10 μM cisplatin for 24 or 48 h before flow cytometry analysis (left). The bar chart (right) shows the ratios of apoptosis cell numbers between the groups treated with the negative control inhibitor, miR-30c inhibitor, negative control inhibitor+cisplatin or miR-30c inhibitor+cisplatin. Data represent the mean of three independent experiments±S.E.M. with n=3. *P<0.05; **P<0.01

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