Figure 2

Dioscin inhibited colony formation and motility in PC3 cells, and reduced the CD133+/CD44+ cells in mammospheres. (a) Effects of dioscin (1.4, 2.8 and 5.6 μM) for 24 h on the colony formation in PC3 cells. (b) Effects of dioscin (0.35, 0.7 and 1.4 μM) for 24 h on the cell motility of PC3 cells. (c) Effects of dioscin (2.5, 5.0 and 10.0 μM) for 24 h on the CD133+/CD44+ cells in PC3 cell-derived mammospheres. Data are presented as the mean±S.D. (n=5). **P<0.01 versus PC3 group; ##P<0.01 versus mammospheres group