Figure 7

Dioscin inhibited tumor growth of cell xenografts in nude mice. (a) Images of the tumors collected from the mice in different groups. (b) Effects of dioscin and ERβ-siRNA on the mean tumor volumes and weights. (c) Effects of dioscin and ERβ-siRNA on tumor histopathology based on H&E staining (× 200 magnification). (d) Effects of dioscin and ERβ-siRNA on ERβ/TUNEL double-staining (× 200 magnification). Data are presented as the mean±S.D. (n=5). *P<0.05 and **P<0.01 versus Control group; NS, not significant