Figure 9 | Cell Death & Disease

Figure 9

From: RETRACTED ARTICLE: Dioscin induces prostate cancer cell apoptosis through activation of estrogen receptor-β

Figure 9

Dioscin promoted the interaction of c-ABL and ERβ, and directly targeted with ERβ. (a) Effects of dioscin on the interaction of c-ABL and ERβ in PC3 cells. (b) The hydrogen bonding model of dioscin and ERβ. (c) Effect of dioscin on ERβ expression level in PC3 cells after transfecting with mutational-ERβ cDNA. (d) Effect of dioscin on the cell viability of PC3 cells after transfecting with mutational-ERβ cDNA. Data are presented as the mean±S.D. (n=5). *P<0.05 and **P<0.01 versus Vehicle group; ##P<0.01, Mutant type (MT) versus wild-type (WT) group

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