Figure 1 | Cell Death & Disease

Figure 1

From: Amlexanox, a selective inhibitor of IKBKE, generates anti-tumoral effects by disrupting the Hippo pathway in human glioblastoma cell lines

Figure 1

Amlexanox inhibited proliferation and colony formation of glioma cells. (a and b) U87 and U251 cells were treated with amlexanox (0–300 μM) for 24, 48, 72 and 96 h, and cell vibility was detected using CCK-8 assay. (c) U87 and U251 cells were treated with various concentrations of amlexanox (0, 50,100 and 150 μM) for 2 weeks. (d) The cell colonies were stained and quantified, and the results are presented in the histogram. The results shown are representative of at least three independent experiments. Data are shown as the mean±S.D. *P<0.05 and **P<0.01 compared with the control group

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