Figure 5
From: TNFα deficiency results in increased IL-1β in an early onset of spontaneous murine colitis
TNFα KO Winnie mice secrete high levels of circulating inflammatory cytokines. Circulating levels of IL-6, IFNγ and IL-1α (a, b and c, respectively) were determined by Bead-based Multiplex assay from serum samples of 5-week-old TNFα KO Winnie and all the control lines. Bars represent mean cytokines concentration±S.E.M. (n=4). Statistical evaluation between C57/Bl6 mice and each murine line was performed using unpaired two-tailed Student’s t-test. ***P<0.001, *P<0.05
