Figure 8 | Cell Death & Disease

Figure 8

From: Long noncoding RNA XIST expedites metastasis and modulates epithelial–mesenchymal transition in colorectal cancer

Figure 8

The functional model underlying the mechanism of lncRNA XIST on CRC tumorigenesis and metastasis. lncRNA XIST sponging to miR-200b-3p through the MRE (microRNA response element); it thus acts as a ceRNA to regulate the expression of ZEB1 and modulate the proliferation, invasion, EMT and stem cell properties in vitro and tumorigenesis and metastasis in vivo

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