Figure 7

Schematic overview of the rat experimental design. (a) Treatment with KW6002 (3 mg/kg) started (orally by gavage) 2 h after retinal ischemia (60 min), and once a day until the end of the experiment (7 days of reperfusion). The green line (a) or the blue line (a and b) indicate the reperfusion time. (b) Caffeine (1 g/l) was administered in the drinking water for 2 weeks prior induction of ischemia (60 min duration) and until the end of the experiment (24 h or 7 days of reperfusion)