Table 1 Parameters evaluated in animals involved in the study
Water-drinking rats | Caffeine-drinking rats | |||||
|---|---|---|---|---|---|---|
Basal | 2 weeks treatment | 3 weeks treatment | Basal | 2 weeks treatment | 3 weeks treatment | |
Fluid intake (ml per day) | 36±3 | 31±4 | 30±2 | 28±1 | ||
Caffeine consumption (mg/kg per day) | 125±7 | 110±9 | ||||
Serum caffeine (μM) | 54.6±20.5 | 97.5±10.7 | ||||
Retinal caffeine/pentoxifylline (ng/mg prot) | 277±25 | 189±26 | ||||
IOP (mmHg) | 11±0.2 | 12±0.5 | 12±0.8 | 12±0.4 | 12±0.3 | 12±1.0 |
