Figure 1
From: Involvement of miR-451 in resistance to paclitaxel by regulating YWHAZ in breast cancer

MiR-451 is downregulated in human BC samples and in PR breast cancer cells. (a) Expression of miR-451 in tumor tissues and matched adjacent normal tissues was revealed by miRNA-seq data provided by analyzing the Cancer Genome Atlas (TCGA) breast cancer miRNA sequencing data sets (normal, n=104; tumor, n=104). (b and c) Real-time RT-PCR assay was performed to detect expression of miR-451 in parental and PR cells. Data are shown as mean±S.D. (n=3). The symbols *, ** and *** represent great significant difference (P<0.05, P<0.01 and P<0.001) by two-tailed Student’s t-test