Figure 2
From: Involvement of miR-451 in resistance to paclitaxel by regulating YWHAZ in breast cancer
Effect of miR-451 on cell migratory, invasive activity in vitro. (a and b) Wound healing assay were performed to compare the migratory potential of SKBR3/PR and MCF-7/PR cells after transfected with miR-451 mimic. Representative image depicting the beginning (t=0 h) and the end (t=24 h) of the recording are shown. Invasion assay was conducted to measure the invasive capacity in SKBR3/PR and MCF-7/PR cells after transfection with miR-451 mimic. (c and d) Wound healing assay was performed to compare the migratory potential of SKBR3 and MCF-7 cells after transfected with miR-451 inhibitor. Representative image depicting the beginning (t=0 h) and the end (t=24 h) of the recording are shown. Invasion assay was conducted to measure the invasive capacity in SKBR3 and MCF-7 cells transfected with miR-451 inhibitor. Bars represent mean±S.D. and asterisks denote a significant difference (*P<0.05; **P<0.01 and ***P<0.001). Data are representative of at least three independent experiments
