Figure 5
From: Involvement of miR-451 in resistance to paclitaxel by regulating YWHAZ in breast cancer
Effect of miR-451 on the mRNA and expression level of β-catenin and downstream targets c-Myc, cyclin D1. (a and b) Real-time RT-PCR analysis and (c and d) western blotting analysis was performed to detect the mRNA levels and expression level of β-catenin, c-Myc and cyclinD1 in SKBR3/PR and MCF-7/PR cells after miR-451 mimics treatment. (e and f) Real-time RT-PCR analysis and (g and h) western blotting analysis was performed to detect the mRNA levels and expression level of β-catenin, c-Myc and cyclinD1 in SKBR3 and MCF-7 cells after miR-451 inhibitors treatment. Bars represent mean±S.D.and asterisks denote a significant difference (*P<0.05; **P<0.01 and ***P<0.001). Data are representative of at least three independent experiments
