Figure 9
From: Involvement of miR-451 in resistance to paclitaxel by regulating YWHAZ in breast cancer
Combination of miR-451 and siRNA-YWHAZ treatment showed enhanced YWHAZ inhibition in vitro. (a) Western blotting analysis was performed to measure the expression of YWHAZ in SKBR3/PR and MCF-7/PR cells after treatment with YWHAZ siRNA or a combination of both. (b and c) Representative images showing effect of different combination treatments on SKBR3/PR and (d and e) MCF-7/PR migration and invasion. Cells were counted in five random fields per well after 24 h for migration and invasion and the percent migratory or percent invasive cells were calculated. The results were showed as mean±S.D. of three independent experiments
