Figure 6 | Cell Death & Disease

Figure 6

From: Activation of miR-34a impairs autophagic flux and promotes cochlear cell death via repressing ATG9A: implications for age-related hearing loss

Figure 6

UDCA protects HEI-OC1 cells from miR-34a mimic-induced cell death. (a) Cell survival experiment was detected in various concentration of UDCA. (b) MiR-34a expression was performed after being treated with or without 10 μM UDCA for 24 h. (c) The MTS assay was performed to examine the viability of HEI-OC1 cells under miR-34a overexpression with or without UDCA treatment. The HEI-OC1 cell viability assessed via MTS assay. (d–g) Western blot analysis and densitometry of LC3-II, p62 and ATG9A. *P<0.05. Date were represented as the mean±S.E.M. obtained from three independent experiments

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