Figure 6 | Cell Death & Disease

Figure 6

From: Regulation of RIP3 by the transcription factor Sp1 and the epigenetic regulator UHRF1 modulates cancer cell necroptosis

Figure 6

Expression of RIP3 in cancer cells represses tumor growth in mouse. (a) Effects of RIP3 overexpression in LL/2 lung cancer cells xenograft in C57BL/6 mice. Tumor volume was monitored and shown in the graph. Data are presented as means±S.D. (n=29). (b) Parts of the tumor issue were fixed and embedded in paraffin, followed by hematoxylin/eosin staining. (c and d) Infiltration of monocytes and neutrophils into the tumor tissues was analyzed by flow cytometry analysis

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