Figure 4 | Cell Death & Disease

Figure 4

From: Long non-coding RNA SNHG20 promotes non-small cell lung cancer cell proliferation and migration by epigenetically silencing of P21 expression

Figure 4

Effect of SNHG20 on NSCLC tumorigenesis in vivo. (a and b) Stable SNHG20-knockdown A549 cells were used for in vivo assays. Growth curves of tumors from two groups of mice injected with A549 cells stably transfected with sh-SNHG20 or empty vectors are shown. Tumor volumes were calculated every 3 days. (c) Tumor weights from the two groups are represented. (d) qRT-PCR was performed to detect the average expression of SNHG20 in xenograft tumors (n=4). (e) Tumors developed from sh-SNHG20-transfected A549 cells showed lower Ki-67 protein levels compared with tumors developed from control cells. Upper: hematoxylin and eosin staining; lower: immunohistochemical staining. *P<0.05, **P<0.01

Back to article page