Figure 2 | Cell Death & Disease

Figure 2

From: Neuron and microglia/macrophage-derived FGF10 activate neuronal FGFR2/PI3K/Akt signaling and inhibit microglia/macrophages TLR4/NF-κB-dependent neuroinflammation to improve functional recovery after spinal cord injury

Figure 2

FGF10 decreases spinal cord tissue damage, motor neuron loss and promotes locomotor recovery after acute SCI in vivo. (a and b) The BBB scores and inclined plane test scores of each group. (c and d) HE staining of each group at 28 days after surgery and quantification data of the percent of cavity necrotic tissue at each interval (scale bar: 200 μm). (e) Nissl staining of each group to test the surviving neurons at 28 days after surgery. Data represent the mean±S.D. Significant differences between the treatment and control groups are indicated as *P<0.05, **P<0.01, n=5

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