Table 1 Endocrine parameters in serum of RU486-induced PCOS and ANP treatment rats

From: ANP promotes proliferation and inhibits apoptosis of ovarian granulosa cells by NPRA/PGRMC1/EGFR complex and improves ovary functions of PCOS rats

 

P (ng/ml)

T (ng/ml)

E 2(pg/ml)

FSH (ng/ml)

LH (mIU/ml)

Control group

438.40±109.42

10.654±1.17

634.63±70.49

210.00±20.55

135.37±26.94

RU486 group

204.78±44.09

16.274±1.25

1247.00±236.80

242.32±28.65

296.40±47.95

ANP group

378.41±13.60

12.48±1.61

895.88±151.45

239.28±34.21

85.07±24.59

P (RU486/Control)

<0.01

<0.001

<0.01

>0.05

<0.001

P (ANP/RU486)

<0.001

<0.01

<0.05

>0.05

<0.001

  1. P: statistical significance (*P<0.05; **P<0.01; ***P<0.001)