Figure 3
From: Current progress in the derivation and therapeutic application of neural stem cells
Therapeutic strategies for the derivation and transplantation of NSCs. MSCs are ideal for NSC derivation because of the ease of accessibility from patient bone marrow and especially subcutaneous adipose tissue. NSCs transdifferentiated from plastic MSCs via non-viral and non-genetic methods, such as induction with small molecules or growth factors, are likely safer for clinical application. Transplantation of derived NSCs or co-transplantation of both cells with or without three-dimensional grafts into patents is dependent on disease-specific targets
