Figure 1
From: Impairment of PTX3 expression in osteoblasts: a key element for osteoporosis
Evaluation of bone morphometric parameters. H&E sections of bone head biopsies (a–c, scale bar represents 4 mm.). (a) OP patients showed a remarkable loss of both trabecular thickness and the number of transversal trabeculae. (b) OA patients display moderate trabecular thinning and decrease of transversal trabeculae, (c) CTRL patients were characterized by a normal trabecular network. Bone quality parameters evaluated by the BioQuant Osteo software: BV/TV, Tb.Th, and Tb.S (d–f) One-way ANOVA BV/TV P<0.0001, Tb.Th P<0,0001, Tb.S P<0,0001 (OP n=25, OA n=25, CTRL n=15). Trabecular, fat and bone were calculated by using digital images (g–i). For each sample, measurements were made at low power magnification
