Figure 3

Effects of PCE on the expression changes of Mig-6 and EGFR in fetal long-bone hypertrophic chondrocytes. (a) ISH of Mig-6 in hypertrophic chondrocytes. (b) Immunostaining of Mig-6 in hypertrophic chondrocytes. (c) Immunostaining of EGFR in hypertrophic chondrocytes. (d) Serum corticosterone (CORT) concentration of fetal rats (ng/ml). (e) Quantification of Mig-6 ISH (fluorescence intensity). (f) Quantification of Mig-6 immunostaining (optical density). (g) Quantification of EGFR immunostaining (optical density). n=5 per group obtained from different litters. Three random fields/section for quantitative. Data are shown as the mean±S.D. *P<0.05, **P<0.01 versus control (ANOVA)