Figure 1
From: PLOD2 regulated by transcription factor FOXA1 promotes metastasis in NSCLC
PLOD2 is closely related to the P-EGFR (epidermal growth factor receptor). (a–e) Kaplan–Meier (KM) analysis of relapse-free survival in lung cancer patients was from KM plotter (http://kmplot.com/analysis). PLOD2 in lung cancer patients (n=1926, a), in lung adenocarcinoma patients (n=719, b), in lung squamous cell carcinoma patients (n=525, c), in lung adenocarcinoma patients at stage I (n=578, d) and in lung adenocarcinoma patients at stage III (n=70, e). (f) The high expression of PLOD2 in tumor tissue of clinical sample by immunohistochemistry (IHC). (g and h) The expression levels of P-EGFR and PLOD2 were consistently analyzed in 33 human lung adenocarcinoma specimens. (i and j) The fibrillate collagen formation and collagen deposition were detected by hematoxylin and eosin (HE) staining and picrosirius red staining in clinical samples
