Figure 3
From: PLOD2 regulated by transcription factor FOXA1 promotes metastasis in NSCLC
PLOD2 increased the migration of the cancer cells. (a and b) The expression of PLOD2 was knocked down by short hairpin RNA (shRNA) in the NCI-H1975 cell line. (c) The proliferation of PLOD2-knockdown cells was evaluated by clone formation. (d) The proliferation of PLOD2-knockdown cells was evaluated in a subcutaneous transplant mouse model. (e and f) The migration of PLOD2-knockdown cells was evaluated by a wound-healing assay. (g and h) The migration of PLOD2-knockdown cells was evaluated by transwell chambers. (i–k) The migration of PLOD2-overexpressing cells was evaluated by transwell chambers
