Figure 6
Functional role of the miR-1/Smad3 axis in regulating tumor glycolysis and proliferation in vivo. In vivo null mice xenograft study. The null mice carrying tumors and tumor sizes was measured for 2 weeks, excised tumor images (a), body weight (b) and tumor volume (c) and tumor weight (d) from respective groups are represented (n=3). Data were presented as mean±s.d. *P<0.05; **P<0.01 and ***P<0.001, Student’s t-test (e) Protein expression in tumor from indicated group was determined by western blotting, for each marker band, values were normalized to internal control and the density of control was set at 1.0
