Table 2 PAK4 expression during colon cancer progression
From: PAK4 regulates G6PD activity by p53 degradation involving colon cancer cell growth
Feature | n | PAK4 expression | P -value | |
|---|---|---|---|---|
Weak | Strong | |||
Age (years) | ||||
 <65 | 84 | 20 | 64 | 0.388 |
 ⩾65 | 70 | 21 | 49 | |
Gender | ||||
 Male | 82 | 23 | 59 | 0.670 |
 Female | 72 | 18 | 54 | |
Tumor size (cm) | ||||
 <5 cm | 76 | 20 | 56 | 0.932 |
 ⩾ 5 cm | 78 | 21 | 57 | |
Histological grade | ||||
 Poorly | 9 | 2 | 7 | 0.003a |
 Moderately | 116 | 24 | 92 | |
 Well | 29 | 15 | 14 | |
Depth of invasion (pT) | ||||
 T1,T2 | 22 | 5 | 17 | 0.656 |
 T3,T4 | 132 | 36 | 96 | |
Lymph node metastasis (pN) | ||||
 No | 105 | 30 | 75 | 0.425 |
 Yes | 49 | 11 | 38 | |
Distant metastasis (pM) | ||||
 No | 139 | 38 | 101 | 0.543 |
 Yes | 15 | 3 | 12 | |
Pathological stage (pStage) | ||||
 Stages I, II | 97 | 32 | 65 | 0.02a |
 Stages III, IV | 57 | 9 | 48 | |
