Table 3 G6PD expression during colon cancer progression
From: PAK4 regulates G6PD activity by p53 degradation involving colon cancer cell growth
Feature | n | G6PD expression | P -value | |
|---|---|---|---|---|
Weak | Strong | |||
Age (years) | ||||
 <65 | 84 | 32 | 52 | 0.390 |
 ⩾65 | 70 | 22 | 48 | |
Gender | ||||
 Male | 82 | 33 | 49 | 0.152 |
 Female | 72 | 21 | 51 | |
Tumor size (cm) | ||||
 <5 cm | 76 | 28 | 48 | 0.649 |
 ⩾5 cm | 78 | 26 | 52 | |
Histological grade | ||||
 Poorly | 9 | 3 | 6 | 0.042a |
 Moderately | 116 | 35 | 81 | |
 Well | 29 | 16 | 13 | |
Depth of invasion (pT) | ||||
 T1,T2 | 22 | 11 | 11 | 0.114 |
 T3,T4 | 132 | 43 | 89 | |
Lymph node metastasis (pN) | ||||
 No | 105 | 39 | 66 | 0.430 |
 Yes | 49 | 15 | 34 | |
Distant metastasis (pM) | ||||
 No | 139 | 50 | 89 | 0.475 |
 Yes | 15 | 4 | 11 | |
Pathological stage (pStage) | ||||
 Stages I, II | 97 | 40 | 57 | 0.037a |
 Stages III, IV | 57 | 14 | 43 | |
