Figure 3 | Cell Death & Disease

Figure 3

From: RASAL2, a RAS GTPase-activating protein, inhibits stemness and epithelial–mesenchymal transition via MAPK/SOX2 pathway in bladder cancer

Figure 3

RASAL2 inhibits EMT of BCa cells. (a) Morphological change of 5637 cells transfected with RASAL2 shRNAs and scramble shRNA. The scale bar is 50μm. Representative pictures and quantification analysis of migration and invasion assays in 5637 cells transfected with RASAL2 shRNAs and scramble shRNA. The scale bar is 100 μm, **P<0.01, ***P<0.001 versus control. (b) Western blotting analysis of EMT markers (E-cadherin, vimentin and ZEB1) in 5637 sublines. (c) Representative pictures and quantification analysis of migration and invasion assays in T24 cells infected with RASAL2 lentivirus and scramble control. The scale bar is 100 μm, **P<0.01, ***P<0.001 versus control. (d) Western blotting analysis of EMT markers (E-cadherin, vimentin and ZEB1) in T24 sublines. GAPDH was used as internal loading control

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